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T cell tumor

Delgoffe Lab: T cell tumor
Oral thrush

Gaffen Lab: Warhol-inspired image of tongues with oropharyngeal candidiasis (‘oral thrush’), covered with the opportunistic fungus Candida albicans
Gut in a dish

The Meisel lab explores mechanisms of how gut bacteria modulate systemic immunity during homeostasis and complex diseases such as autoimmunity and cancer
Multispectral imaging captures hallmarks of tertiary lymphoid structures (TLS)

Bruno Lab: TLS activity in ovarian cancer is driven by site and stroma
Immune regulation in tumors

Vignali Lab: Immune Infiltrates in Breast Cancer (CD20- cyan, CD4- green, CD8- orange, CD68- red, Foxp3- yellow, PanCK- magenta, DAPI- blue)
Protein capture in lymph nodes

Binder Lab: Intradermal immunization with gp96 leads to its localization in CD11b⁺CD11c⁺ cells in the draining lymph node.

Mission

The mission of the Department of Immunology is to discover new mechanisms and pathways of the immune system to enrich human health by combating and preventing disease, enhancing vaccination, and controlling autoimmunity. The department has a mission of training students, post-doctoral fellows, physicians, and other young scientists to be proficient in immunology.

Global Impact

From Jonas Salk's discovery of the polio vaccine in the 1950s to ongoing research on immune system mechanisms and pathways, Pitt immunologists have profoundly improved human health.

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